Investigation on Annotation of Children’s Medication Information in Instructions of Commonly Used Drugs for Children in Outpatients of a Hospital

Guo Zhiye; Li Lingling; Chu Zhijun; Zhang Xiaoxu; Qi Huihong; Zhou Hang; Jiao Wanli

doi:10.13407/ j.cnki. jpp.1672-108X.2022.06.009

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Investigation on Annotation of Children’s Medication Information in Instructions of Commonly Used Drugs for Children in Outpatients of a Hospital

更新时间：2022-11-04

- Investigation on Annotation of Children’s Medication Information in Instructions of Commonly Used Drugs for Children in Outpatients of a Hospital
- Vol. 28, Issue 6, Pages: 33-37(2022)
- 作者机构：
  
  唐山市工人医院,河北,唐山,063000
- 作者简介：
- 基金信息：
- DOI：10.13407/ j.cnki. jpp.1672-108X.2022.06.009
  CLC：
- Published：2022，
  
  Published Online：10 June 2022，
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Guo Zhiye, Li Lingling, Chu Zhijun, et al. Investigation on Annotation of Children’s Medication Information in Instructions of Commonly Used Drugs for Children in Outpatients of a Hospital. [J]. 28(6):33-37(2022)
DOI：

Guo Zhiye, Li Lingling, Chu Zhijun, et al. Investigation on Annotation of Children’s Medication Information in Instructions of Commonly Used Drugs for Children in Outpatients of a Hospital. [J]. 28(6):33-37(2022) DOI： 10.13407/ j.cnki. jpp.1672-108X.2022.06.009.

摘要

目的：调查某院门诊儿童常用药品说明书中有关儿童用药信息的标注情况，为药品说明书的完善和临床合理用药提供参考。方法：通过临床药学管理系统收集2020年4月至2021年3月某院门诊儿童患者（<16岁）处方中的药品，对药品说明书中的儿童用药信息标注情况进行调查分析。结果：全部药品（403个品种）说明书中标注儿童用药问题（包括禁用和不推荐使用）的药品说明书有72个（17.87%）；儿童常用药品（143个）说明书中明确儿童用药剂量、儿童用药指导、儿童药物代谢动力学、儿童临床试验的标注率分别是35.66%、57.34%、9.79%、5.59%，其中最常用的药理学（功能）类别中，西药消化系统用药、免疫系统用药、皮肤科用药以及中成药内科用药的标注率较低，剂型类别中口服制剂的标注率较低，处方药非处方药类别中非处方药的标注率较低；儿童用药剂量确定方法中最常用的是固定剂量和按体质量确定剂量。结论：门诊儿童患者用药中涉及到儿童用药问题药品品种数量较多，且常用药品说明书中有关儿童用药信息的标注率不佳，应在临床使用时加强管理，并不断完善药品说明书，从而保障儿童用药安全合理。

Abstract

Objective: To investigate the annotation of children’s medication information in instructions of commonly used drugs for children in outpatients of a hospital

so as to provide reference for the improvement of drug instructions and rational drug use in clinic. Methods: Through the clinical pharmacy management system

drugs in prescriptions of outpatient pediatric patients (less than 16 years old) in a hospital from Apr. 2020 to Mar. 2021 were collected

and the annotation of children’s medication information in the drug instructions was investigated and analyzed. Results: There were 72 (17.87%) kinds of drugs had medication problems in children (including banned and not recommended drugs) in all drug instructions (403 categories). The annotation rates of drug dosage

drug guidance

pharmacokinetics and clinical trials in children in commonly used drug instructions (143 categories) were respectively 35.66%

57.34%

9.79% and 5.59%. Among the most commonly used pharmacological (functional) categories

the annotation rate of western drugs for digestive system

immune system

dermatology and internal medicine of Chinese patent medicine was relatively low

the annotation rate of oral preparations in dosage form category was relatively low

and the annotation rate of ethical drug and over the counter (OTC) drug category was relatively low. The most commonly used methods of dose determination for children were fixed dose and dose determination by body mass. Conclusion: There are a large number of problems related to children’s medication in outpatient pediatric patients

and the annotation rate of children’s medication information in commonly used drug instructions is lower. Therefore

it is necessary to strengthen the management in clinical use and constantly improve the drug instructions

so as to ensure the safety and rationality of children’s medication.

关键词

儿童药品说明书标注率合理用药

Keywords

childrenrug instructionsannotation raterational drug use

references

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